Acute mixed lineage leukemia: clinicopathologic correlations and prognostic significance
نویسندگان
چکیده
منابع مشابه
Acute mixed lineage leukemia: clinicopathologic correlations and prognostic significance.
The frequency and clinical significance of acute leukemia displaying both lymphoid and myeloid characteristics was determined in 123 consecutive children using a panel of lineage-associated markers. The leukemic blasts from 18 of 95 children (19%) with the diagnosis of acute lymphoblastic leukemia (ALL) by standard diagnostic criteria expressed myeloid-associated cell surface antigens. Despite ...
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BACKGROUND The overall prognosis of acute myeloid leukemia (AML) patients with mixed-lineage leukemia (MLL) gene-positivity is unfavorable. In this study, we evaluated the expression levels of the MLL gene in AML patients. MATERIAL AND METHODS We enrolled 68 MLL gene-positive patients out of 433 newly diagnosed AML patients, and 216 bone marrow samples were collected. Real-time fluorescence qua...
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A recent report by Pui et all focused on the biologic and clinical relevance of acute mixed-lineage leukemia; namely, acute lymphoblastic leukemia expressing myeloid-associated antigens (My+ ALL) and acute myeloid antigens expressing lymphoid antigens (Ly+ AML) were analyzed in a pediatric series. In our opinion, a major point in the field of hybrid acute leukemia remaining undetermined is whic...
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A recent report by Pui et all focused on the biologic and clinical relevance of acute mixed-lineage leukemia; namely, acute lymphoblastic leukemia expressing myeloid-associated antigens (My+ ALL) and acute myeloid antigens expressing lymphoid antigens (Ly+ AML) were analyzed in a pediatric series. In our opinion, a major point in the field of hybrid acute leukemia remaining undetermined is whic...
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ژورنال
عنوان ژورنال: Blood
سال: 1985
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v66.5.1115.1115